Fig 1: Representative images of high-grade neuroendocrine carcinoma of the lung. (a) Hematoxylin and eosin staining (H&E) and c-MYC immunohistochemistry (IHC) of small-cell lung carcinoma. The nuclei of carcinoma were positive for c-MYC. (b) H&E and n-MYC IHC of large-cell neuroendocrine carcinoma (LCNEC). The nuclei of carcinoma were positive for n-MYC. (c) H&E and l-MYC IHC of LCNEC. The nuclei of carcinoma were positive for l-MYC. Original magnification is ×400 for H&E and IHC